[Experience with lamictal in the treatment of outpatients with resistant epilepsy] Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova / Ministerstvo zdravookhraneniia i meditsinskoĭ promyshlennosti Rossiĭskoĭ Federatsii, Vserossiĭskoe obshchestvo nevrologov [i] Vserossiĭskoe obshchestvo psikhiatrov. [Zh Nevrol Psikhiatr Im S S Korsakova] Journal article | | Title | [Experience with lamictal in the treatment of outpatients with resistant epilepsy] | | Author(s) | Perunova NIu, Sorokina EV, Shershever AS | | Source | Zh Nevrol Psikhiatr Im S S Korsakova 2003; 103(1):30-4. | | MeSH | Adult
Anticonvulsants
Drug Administration Schedule
Drug Resistance
English Abstract
Epilepsy
Female
Humans
Male
Middle Aged
Time Factors
Triazines
| | Abstract | The article summarizes the results of lamictal treatment in 93 patients with resistant epilepsy. Lamictal was used in a dose of 50-200 mg a day as an auxiliary drug in the treatment with other anticonvulsants. Its therapeutic efficacy was analyzed in relation to the form of epilepsy, the type of seizures, dosage of lamictal duration of therapy, and as patients' sex, age, and social activity. In the total group, 17.2% of the patients have remissions, in 48.4% the frequency of seizures frequency was reduced (> 50%) and 34.4% of the patients exhibited a less pronounced effect (< 50%). When combining lamictal and valproates, the best results were obtained in generalized seizures, especially in idiopathic generalized epilepsy, and in young and middle-age female patients with active social functioning. | | Language | rus | | Pub Type(s) | Journal Article
| | PubMed ID | 12616735 |
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